With the Sudachi model it’s easy to achieve high quality flat 2d anime images.
☆Use mostly danbooru tags. No extra vae needed.
➤ Use clip skip 2 with sampler DPM++ 2M Karras or DDIM.
➤ Use "R-ESRGAN 4x+ Anime6B" as upscaler, if you want to remain on a flat style
☆
https://civitai.com/models/85909/sudachi. ☆